Ova Balance · 1,500+ studies
Myo-Inositol
A sugar alcohol the body makes and also gets from food, central to how cells read the insulin signal. In the ovary it is part of the FSH signalling pathway, which is why it is the most-studied nutritional agent in PCOS research.
The form we use
Pharmaceutical-grade myo-inositol powder, dosed in a 40:1 ratio with D-chiro inositol
The published PCOS literature is built on gram-level myo-inositol doses in the physiological 40:1 myo to D-chiro ratio — the ratio found in healthy plasma. Capsule formats rarely reach that dose without a large pill count, so TruWe delivers it as a single daily sachet at 2000 mg myo-inositol with 50 mg D-chiro inositol.
Why this form
How the common forms compare
| Form | What published literature reports | In TruWe |
|---|---|---|
| Myo-inositol alone | Widely studied, but does not supply the D-chiro component of the physiological ratio. | Not used |
| Myo : D-chiro 40:1 | The plasma ratio used across the modern inositol trial literature. | Used |
| High D-chiro ratios (e.g. 1:1) | Literature discusses an ovarian 'D-chiro paradox' at disproportionate D-chiro exposure. | Not used |
| Low-dose inositol capsules | Convenient, but typically well below the gram-level doses used in published trials. | Not used |
Dose
Where it appears, and how much
Ova Balance
2000 mg
with 50 mg D-chiro inositol · 40:1
View product →
The evidence
What the research says
Restores insulin signalling, ovulation and cycle regularity — backed by the research-backed 40:1 Myo:D-Chiro ratio.
Reference researcher: Prof. Vittorio Unfer · Experts Group on Inositol in Basic & Clinical Research
- Myo-inositol in patients with polycystic ovary syndrome: a novel method for ovulation induction
Gynecological Endocrinology · 2007
- A comparative study between myo-inositol and metformin in the treatment of insulin-resistant women with PCOS
European Review for Medical & Pharmacological Sciences · 2017
- Short-term effects of metformin and myo-inositol in women with PCOS: a meta-analysis
Gynecological Endocrinology · 2019
- Myo-inositol effects in women with PCOS: a meta-analysis of randomized controlled trials
Endocrine Connections · 2017
Questions, answered
Myo-Inositol FAQ
- Why a sachet instead of capsules?
- The studied dose is measured in grams. Delivering 2050 mg of inositol complex in capsules would mean several large capsules a day.
- What does the 40:1 ratio mean?
- Forty parts myo-inositol to one part D-chiro inositol — the ratio reported in healthy human plasma and used in the modern trial literature.
- How long before anything changes?
- Published PCOS trials typically run three to six months. Treat it as a protocol, not a quick fix.
- Can I take it with metformin?
- Several published studies compare or combine the two, but that is a decision for your doctor — not something to start on your own.
- Is inositol a hormone?
- No. It is a carbocyclic sugar involved in cell signalling, not a hormone.
Ingredient-level research is published on the individual actives and their delivery forms. It describes the ingredients, not a finished-product claim. These statements have not been evaluated by the FSSAI or FDA. This content is for information only and is not medical advice.
← All ingredients
