Mag Absorb Pro · 300+ studies
Magnesium Bisglycinate
Magnesium bound to two molecules of the amino acid glycine (a bisglycinate chelate). The chelate keeps the mineral bound as it moves through the gut, which is why this form is the one most commonly studied for sleep, stress and relaxation rather than for laxative effect.
The form we use
Liposomal magnesium bisglycinate (fully reacted chelate, phospholipid-encapsulated)
Inorganic magnesium salts such as oxide are cheap and high in elemental magnesium by weight, but comparative pharmacokinetic work reports substantially lower absorption for oxide than for the diglycinate chelate. TruWe uses the fully reacted bisglycinate chelate — the form used in the sleep and anxiety literature — and pairs it with a phospholipid (liposomal) carrier used across the delivery-science literature to protect actives through digestion.
Why this form
How the common forms compare
| Form | What published literature reports | In TruWe |
|---|---|---|
| Magnesium oxide | High elemental magnesium per gram, but comparative studies report poor absorption and a strong osmotic/laxative effect. | Not used |
| Magnesium citrate | Better absorbed than oxide; widely used, but commonly associated with loose stools at higher doses. | Not used |
| Magnesium bisglycinate (diglycinate) | Amino-acid chelate; comparative bioavailability work reports higher absorption than oxide with better gastrointestinal tolerance. The form used in insomnia and stress trials. | Used |
| Liposomal magnesium bisglycinate | The same chelate carried in a phospholipid matrix — the delivery approach used in published liposomal-nutrient pharmacokinetics. | Used |
Dose
Where it appears, and how much
Mag Absorb Pro
200 mg
elemental magnesium · Phase 3 of the 5-form matrix
View product →Ova Balance
100 mg
elemental magnesium · mineral cofactor
View product →
The evidence
What the research says
Highly bioavailable, gentle-on-gut chelate — the gold standard for relaxation, sleep onset and stress recovery.
Reference researcher: Dr. Stella Lucia Volpe · Virginia Tech
- Bioavailability of magnesium diglycinate vs magnesium oxide in patients with ileal resection
JPEN: Journal of Parenteral & Enteral Nutrition · 1994
- The effects of magnesium supplementation on subjective anxiety and stress — a systematic review
Nutrients · 2017
- Magnesium status and stress: the vicious circle concept revisited
Nutrients · 2020
- Effect of magnesium supplementation on primary insomnia in elderly: a double-blind placebo-controlled RCT
Journal of Research in Medical Sciences · 2012
Questions, answered
Magnesium Bisglycinate FAQ
- Why not magnesium oxide, the cheapest form?
- Oxide looks strong on the label because it carries a lot of elemental magnesium by weight, but comparative absorption studies report that far less of it actually reaches circulation, and it is the form most associated with a laxative effect.
- Is bisglycinate the same as glycinate?
- Yes — bisglycinate (diglycinate) means one magnesium ion bound to two glycine molecules. 'Magnesium glycinate' on a label usually refers to the same chelate.
- What does liposomal add?
- A phospholipid carrier around the active. It is the delivery approach used in published liposomal-nutrient pharmacokinetic studies to protect the payload through digestion.
- How much elemental magnesium does Mag Absorb Pro give?
- 440 mg elemental magnesium across five forms per 2-tablet daily serving; magnesium bisglycinate contributes 200 mg of that.
- When should I take it?
- Evening is the usual choice, because the sleep and relaxation research on magnesium is built around evening dosing.
- Will it upset my stomach?
- Chelated forms are generally chosen for tolerability. If you are sensitive, take it with food and start with the standard serving rather than doubling it.
Ingredient-level research is published on the individual actives and their delivery forms. It describes the ingredients, not a finished-product claim. These statements have not been evaluated by the FSSAI or FDA. This content is for information only and is not medical advice.
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